The FDA just released its most comprehensive drug-drug interaction report ever, with the findings showing that many prescription drugs and cosmetics are laced with harmful substances.
Here are some of the highlights:In 2016, nearly two-thirds of prescription drugs tested positive for at least one of the potentially harmful substances, including oxycodone and hydrocodone, according to the FDA.
That number jumps to nearly 70 percent in 2017 and more than 90 percent in 2018.
For the most part, the FDA said, these drugs were found in cosmetics, including nail polish, lotions, and toothpaste.
And more than half of prescription-drug-related deaths involve prescription-grade drugs.
The FDA reported that more than 80 percent of prescription medications tested positive in 2017, compared to roughly 50 percent in 2016.
The FDA also found that more prescription drugs than ever tested positive, with more than 3,500 prescription drugs found to contain at least 25 different potentially harmful chemicals.
And a whopping 80 percent tested positive at least once.
The agency’s report comes just a few weeks after the FDA revealed that almost half of all prescription drugs in use around the country tested positive.
And that figure rose to almost 90 percent last year.
And while the number of deaths linked to prescription drugs spiked in 2016, the rate has fallen slightly over the past year, with only 2,824 deaths from prescription drugs last year, compared with 7,933 deaths from heroin, fentanyl, and methadone in 2016 and 4,865 deaths from oxycodones in 2017.
Here’s the full list of the prescription drugs the FDA found in 2016: Oxycodone (opioid) Naloxone (naloxodone) Fentanyl (fentanyl) Methadone (methadolone)Hydrocodones (hydrocodoxine)Advil (advil)Naltrexone (narcan)Codeine (codeine hydrochloride)Sulpiride (sulpirid)DosageFor the most common drugs tested, the average drug was tested for 0.7 grams of the drug, and the average dosage was 4.8 milligrams per day.
In the case of Oxycodone, the drug was found to be 0.5 grams per dose, with an average dose of 4.1 milligram.
The average dose for all prescription-based drugs was 4 milliggrams.
The average drug tested positive twice: once in 2017 for oxycodolone and once in 2018 for hydrocodyne.
In 2018, nearly 1 in 4 prescription-related fatalities were linked to oxycodine.
More than half were linked by a drug called Naloxon, a synthetic opioid that’s been linked to overdose and death.
The data was compiled using data from the FDA’s Drug Enforcement Administration database, which is administered to the agency by the Drug Enforcement Agency’s Center for Drug Evaluation and Research.
The drug database is used to identify drugs that are most frequently used by Americans and to monitor and report the safety and efficacy of prescription drug products.
The DEA said that the FDA will continue to conduct this analysis, and that it will update the report in the future.